Changing Selective Pressure during Antigenic Changes in Human Influenza H3
نویسندگان
چکیده
منابع مشابه
Changing Selective Pressure during Antigenic Changes in Human Influenza H3
The rapid evolution of influenza viruses presents difficulties in maintaining the optimal efficiency of vaccines. Amino acid substitutions result in antigenic drift, a process whereby antisera raised in response to one virus have reduced effectiveness against future viruses. Interestingly, while amino acid substitutions occur at a relatively constant rate, the antigenic properties of H3 move in...
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ژورنال
عنوان ژورنال: PLoS Pathogens
سال: 2008
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1000058